Research Articles
From Pixels to Prognosis: How Deep Learning is Revolutionizing Neuroimaging Analysis
This article provides a comprehensive guide to deep learning (DL) applications in neuroimaging for researchers and biomedical professionals.
Identifying and Mitigating Analytical Bias in Neuroimaging Pipelines: A Practical Guide for Neuroscience Researchers and Pharma R&D
This article provides a comprehensive framework for understanding and addressing analytical bias in neuroimaging processing pipelines, tailored for researchers, scientists, and drug development professionals.
Precision Control of Reward: A Comprehensive Guide to DREADD-Based Manipulation of Dopaminergic Circuits
This article provides a detailed technical resource for researchers, scientists, and drug development professionals on the use of Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) for targeted manipulation of...
DCM Comparison for Neurotransmitter Hypotheses: A Framework for Computational Psychiatry and Drug Development
This article provides a comprehensive comparison of Dynamic Causal Modeling (DCM) frameworks used to test neurotransmitter hypotheses in psychiatric and neurological disorders.
Navigating DCM for fMRI Model Selection: Challenges, Solutions, and Best Practices for Neuroscientists
This article provides a comprehensive guide to the significant challenges in Dynamic Causal Modeling (DCM) for fMRI model selection, a critical step for inferring effective brain connectivity.
Unlocking the Social Brain: A Comprehensive Guide to the DCM PEB Framework for Neuroscientists and Drug Developers
This article provides a detailed exploration of the Dynamic Causal Modeling for Parametric Empirical Bayes (DCM PEB) framework and its transformative application in social neuroscience and neuropsychiatric drug development.
Precision Targeting in DBS: Advances in Internal Capsule and Nucleus Accumbens Localization for Therapeutic Development
This article provides a comprehensive technical analysis for researchers and drug development professionals on Deep Brain Stimulation (DBS) targeting of the nucleus accumbens (NAc) via the anterior limb of the...
A Comprehensive Guide to DBS Evoked Potential Protocols: Standardizing Biomarker Measurement for Therapy and Research
This article provides a detailed, state-of-the-art guide for researchers and clinicians on measuring evoked potentials (EPs) as biomarkers in Deep Brain Stimulation (DBS).
DAT-SPECT Imaging: A Comprehensive Guide to Assessing Presynaptic Nigrostriatal Terminal Function in Neurodegeneration
This article provides a comprehensive analysis of DAT-SPECT imaging as a critical tool for quantifying the integrity of presynaptic dopaminergic terminals in the nigrostriatal pathway.
D1 vs. D2 Dopamine Receptors: Distinct Molecular Mechanisms and Behavioral Functions in Reward Processing
This review synthesizes current research on the distinct and often opposing roles of dopamine D1- and D2-like receptors in reward-related behaviors.