Research Articles
Genetically Encoded Dopamine Sensors: A Comprehensive Guide for Neuroscience Research and Drug Development
This article provides a comprehensive overview of genetically encoded fluorescent sensors for dopamine imaging, a revolutionary technology enabling high-resolution analysis of neurochemical dynamics.
Advanced Microdialysis Protocols for Extracellular Neurotransmitter Sampling: A Comprehensive Guide for Preclinical Research
This article provides a comprehensive guide to in vivo microdialysis for sampling neurotransmitters in the brain extracellular space.
Closed-Loop Deep Brain Stimulation for Parkinson's Disease: Mechanisms, Clinical Translation, and Future Directions
Closed-loop deep brain stimulation (aDBS) represents a paradigm shift in the treatment of Parkinson's disease (PD), moving from continuous, open-loop stimulation to dynamic, biomarker-driven neuromodulation.
Magnetic Resonance Spectroscopy for Glutamate Quantification: Techniques, Applications, and Best Practices for CNS Research
This article provides a comprehensive resource for researchers and drug development professionals on in vivo glutamate quantification using proton magnetic resonance spectroscopy (¹H-MRS).
Illuminating the Brain: A Comprehensive Guide to Protein-Based Fluorescent Probes for Neurotransmitter Imaging
This article provides a comprehensive overview of the development, application, and future of protein-based fluorescent probes for imaging neurotransmitters.
Fast-Scan Cyclic Voltammetry for Adenosine Detection: Principles, Advances, and Clinical Translation
This article provides a comprehensive resource for researchers and drug development professionals on the application of Fast-Scan Cyclic Voltammetry (FSCV) for detecting the neuromodulator adenosine.
Combined fMRI-MRS: A Revolutionary Tool for Direct Neurochemical Measurement in Neuroscience and Drug Development
This article explores the transformative potential of combined functional Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy (fMRI-MRS), a novel neuroimaging method that enables the simultaneous acquisition of hemodynamic (BOLD-fMRI) and...
Neurotransmitter-Controlled Steroid Hormone Receptors in the CNS: Mechanisms, Methods, and Therapeutic Targeting
This article synthesizes current knowledge on the intricate crosstalk between neurotransmitters and steroid hormone receptors in the central nervous system, a rapidly advancing field with profound implications for neuropharmacology and...
Neural Control of Muscle Neurochemistry: From Molecular Mechanisms to Therapeutic Innovation
This article synthesizes contemporary research on the intricate biochemical crosstalk between the nervous system and muscle tissue.
Decoding Dopine Signaling: Neural Circuits, Reward Mechanisms, and Therapeutic Frontiers
This comprehensive review synthesizes current research on dopamine signaling pathways and their pivotal role in reward processing, motivation, and adaptive behavior.